Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
O14782
UPID:
KIF3C_HUMAN
Alternative names:
-
Alternative UPACC:
O14782; O43544; Q4ZG18; Q53SX5; Q562F7
Background:
Kinesin-like protein KIF3C plays a pivotal role in cellular mechanics and intracellular transport. It is a microtubule-based anterograde translocator, essential for the movement of membranous organelles. This protein's intricate involvement in cellular transport mechanisms underscores its importance in maintaining cellular function and integrity.
Therapeutic significance:
Understanding the role of Kinesin-like protein KIF3C could open doors to potential therapeutic strategies. Its critical function in cellular transport and mechanics positions it as a key target for interventions in diseases where these processes are disrupted.