Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P02743
UPID:
SAMP_HUMAN
Alternative names:
9.5S alpha-1-glycoprotein
Alternative UPACC:
P02743
Background:
Serum amyloid P-component, also known as 9.5S alpha-1-glycoprotein, plays a crucial role in the body's immune response. It has the ability to interact with DNA and histones, scavenging nuclear material from damaged cells. Additionally, it functions as a calcium-dependent lectin, indicating its involvement in various cellular processes.
Therapeutic significance:
Understanding the role of Serum amyloid P-component could open doors to potential therapeutic strategies. Its unique ability to bind to nuclear material and function as a lectin highlights its potential as a target for drug discovery, aiming to modulate immune responses or clear damaged cellular components.