Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q14061
UPID:
COX17_HUMAN
Alternative names:
-
Alternative UPACC:
Q14061; B2R5D2; D3DN84; Q3MHD6
Background:
The Cytochrome c oxidase copper chaperone plays a pivotal role in cellular energy production, facilitating the assembly of the mitochondrial respiratory chain complex IV. This protein binds two copper ions, essential for the activation of cytochrome c oxidase, a key enzyme in the electron transport chain that drives ATP synthesis.
Therapeutic significance:
Understanding the role of Cytochrome c oxidase copper chaperone could open doors to potential therapeutic strategies. Its critical function in energy metabolism positions it as a potential target for addressing mitochondrial disorders and enhancing cellular bioenergetics in disease states.