Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9BYV2
UPID:
TRI54_HUMAN
Alternative names:
Muscle-specific RING finger protein; Muscle-specific RING finger protein 3; RING finger protein 30
Alternative UPACC:
Q9BYV2; A5D8T7; Q53SY4; Q9BYV3
Background:
Tripartite motif-containing protein 54, also known as Muscle-specific RING finger protein, plays a crucial role in myotubes formation by potentially binding and stabilizing microtubules. This protein, identified by the accession number Q9BYV2, is pivotal in muscle cell structure and function.
Therapeutic significance:
Understanding the role of Tripartite motif-containing protein 54 could open doors to potential therapeutic strategies. Its involvement in muscle cell formation and stabilization highlights its importance in muscle physiology and potential muscle-related disorders.