Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9NQX4
UPID:
MYO5C_HUMAN
Alternative names:
-
Alternative UPACC:
Q9NQX4; Q6P1W8
Background:
Unconventional myosin-Vc plays a pivotal role in cellular processes, primarily through its involvement in transferrin trafficking. This protein is essential for the actin-based membrane trafficking that occurs in various critical tissues, ensuring proper cellular function and homeostasis.
Therapeutic significance:
Understanding the role of Unconventional myosin-Vc could open doors to potential therapeutic strategies. Its crucial involvement in membrane trafficking highlights its potential as a target for interventions in diseases where cellular transport mechanisms are disrupted.