Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q9UMY4
UPID:
SNX12_HUMAN
Alternative names:
-
Alternative UPACC:
Q9UMY4; F8W8K5; Q8WUG9
Background:
Sorting nexin-12 plays a crucial role in intracellular trafficking, a process vital for cellular communication and nutrient transport. This protein's involvement in multiple stages of trafficking underscores its importance in maintaining cellular function and homeostasis.
Therapeutic significance:
Understanding the role of Sorting nexin-12 could open doors to potential therapeutic strategies. Its pivotal role in intracellular trafficking suggests that modulating its activity could influence cellular processes fundamental to health and disease.